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    NuTriVene-D Advanced Antioxidant Daily Supplement (Capsules) - NEW FORMULA


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    New Formulation Now Available!

    We are pleased to announce the following revisions to the Nutrivene-D Daily Supplement formulas. Many of the formula revisions were made to address the insufficiencies of the methylation pathways in Down syndrome.  For updated Nutrition Profile information on Nutrivene-D products, click here.


    Added P5P as B6 ingredient source – helps complement the activity of Pyridoxal Phosphate

    Added Zeaxanthin - this Carotenoid essential for eye development and retinal function*

    Added Boron – helps support Calcium and Magnesium, especially for bone development*

    Added Quercetin to replace Citrus Bioflavonoids - more effective in clinical trials

    Added Silicon – helps support tissue and bone integrity*

    Ingredient Source Revisions

    Changed Vitamin E source to Alpha Tocopherol – better absorption

    Changed Folic Acid source to Folate source Methyltetrahydrofolate, glucosamine salt - source better converted to 5-MTHF

    Changed B12 source to Methylcobalamim - most abundant, active B12 in body, dose also increased for better oral absorption

    Changed Chromium source to Picolinate - best clinically documented source for blood sugar

    Changed Magnesium source to Magnesium Glycinate - highly absorbable and contributes glycine for cell glutathione production

    Changed Selenium source to Selenite – most non-allergenic source


    Increased Manganese - essential for SOD and metabolism of cholesterol, carbohydrates, and amino acids

    Increased Potassium - to obtain higher amount of daily recommended value


    Reduced Niacinamide level - reduced to alleviate possible side effects of higher intake levels

    Reduced Choline Bitartrate - amount reduced based on estimated daily value individuals consume

    Removal of Ingredients

    Removed Carotenoids - not reliably converted to Vitamin A

    Removed L-Citrulline - no evidence for clinical benefit as dietary supplement

    Removed Methionine – can deplete Folate and B12

    Removed Serine - no clinical basis for ingredient

    Removed Lycopene - early evidence for clinical benefit hasn't held up

    Removed Mesa Inositol - no proven clinical benefit

    Removed Papain – could be allergenic

    Removed Bromelain – could be allergenic

    Removed Paba - no proven benefit from oral intake

    Some dosages have been revised slightly so please review the new directions for use included with your order.

    This product is GMO-free and gluten-free.

    The newly reformulated Nutrivene-D Advanced Antioxidant Daily Supplement contains over 40 vitamins, minerals, and antioxidants including Zinc, Selenium, Coenzyme Q10, Alpha Lipoic Acid, Glutathione, Bioflavonoids, Vitamins A, C, and E.

    Some nutrients may aid in the metabolic disturbances in Down syndrome (1,2,3,4,5). These metabolic disturbances are thought to include the disruption of methylation pathways (SAM cycle), connective tissue issues which result in hypotonia, and the overexpression of the superoxide dismutase gene which may cause oxidative stress and accelerated aging. A study conducted on Nutrivene-D in children with Down syndrome noted a reduction of infections, improved growth, and improvements in laboratory parameters (Vitamins A, E, Selenium, etc.). Parents and therapists involved in the study reported considerable improvements in behavior, cooperation, and development of the children administered Nutrivene (6). The Nutrivene-D Daily Supplement in Capsule form contains 252 capsules which may be swallowed or pulled apart and added to foods or drinks.

    (1) J Neurol 2002 Oct;249(10):1347-56 (2) Am J Hum Genet 2001 Jul;69(1):88-95 (3) Bio Trace Elem Res 2001 Jul;81(1):21-8 (4) Int J Clin Pharmacol Res 2001;21(2)79-84 (5) Mutat Res 1993 Aug;295(3):105-11 (6) Padiat Prax 2001;59:703-708